![]() The elasticity modulus of the hybrid material is found to depend on scaffold’s thickness, with the lowest value of 13 GPa obtained in samples containing the highest number of alternating layers. By exploiting the rich reactivity of the GO’s basal epoxydic and edge carboxylate moieties when interacting, respectively, with NH 2 and NH 3 + groups of linear polyethylenimines (PEIs), 3D architectures with variable thickness and porosity can be manufactured, making use of the layer-by-layer technique through the subsequent dipping in GO and PEI aqueous solutions, thereby attaining enhanced compositional and structural control. Such unique characteristics can collectively be found in hybrid, highly porous tridimensional scaffolds based on chemically functionalized graphene oxide (GO). The development of novel three-dimensional (3D) nanomaterials combining high biocompatibility, precise mechanical characteristics, electrical conductivity, and controlled pore size to enable cell and nutrient permeation is highly sought after for cardiac tissue engineering applications including repair of damaged heart tissues following myocardial infarction and heart failure. ![]()
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